"Now we can rationally design drugs that enhance bortezomib's action and favor NOXA production," she says. "Improvements might make it possible to give lower doses of the drug for a shorter time." [Medical News Today]
I for one would like to take significantly less bortezomib. It feels like there is a bit too much programed cell death going on in my muscles (and head.) The UM study focused on melanoma which I should now have a much lower chance of ever developing. Ye ha.
If the folks at MIT could just Remote-Control a few billion Nanoparticles to Deliver Drugs Directly Into my laughing plasma cells I'd be all set.
2 comments:
What about cancer cells?
Velcade has very little known efficacy against MM stem cells. NOXA is also not expressed by stem cells in general but I am not sure about MM stem cells in specific.
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