Wednesday, December 31, 2008

Freezing Fog

According to the Weather Underground this morning we are experiencing: Freezing Fog with Active Advisories: Winter Storm Warning, Flood Warning, Special Weather Statement (US Severe Weather), Active Notice: Record Report, Public Information Statement

Just what is freezing fog? This looks like snow to me, but I guess if it is thick enough then you can call it freezing fog. Why not flaking fog? How about falling frozen fog with significant accumulation of fallen frozen fog particulate? Now not a mere 15 minutes later we have freezing sunshine.

I learned on Monday from the lead author of the early December presentation at ASH on GRN163L that yes indeed the Telomerase activity in the bulk tumor fraction of my bone marrow decreased by 78%. Yet another reason which I forgot to mention earlier to party tonight.

If you're going to be able to look back on something and laugh about it, you might as well laugh about it now.” Marie Osmond

Its Party Time

Marlee is no longer captivated by the scene changes in the Nutcracker Suite. I on the other hand am still in awe of my response to Rev/Dex. I am now in the 90% response range. Every single CBC, CMP, LDH, CRP... is in the normal range except a slight anemia, antibody suppression and an elevated lambda free light chain and related lambda/kappa ratio. (My M-spike is negligible)

The orthopedic surgeon said he didn't need to see me again. "Go do some strength training on that arm."

The oncologist said: "No More Dex!!"

It is definitely Party Time Tonight!

Wednesday, December 10, 2008

Meet the Man's

That would be Ginger and Brad Man (the "e" is silent in Bread). We made the front page photo scroll on which is were I got the attached image

I guess that is not as dorky as the Man's making out in the elevator. Today is another dex day so either I ramble with no point or just stop and move on to some other urgent project which I will abandon shortly after finding an even more urgent project. Oh ya I have a final exam that needs some work.

Monday, December 08, 2008


Sorry, but I don't have any dorky pictures of Lu and I as the happy couple, The Man's. That would be Ginger and Bread. What a wonderful event though. So wonderful in fact we are now the proud owners of a new house. It so reminded us of our summer place that we could not pass it up. A couple of students (I assume culinary artists!) started on it about a month ago. She filled the inside with goodies likes cakes, croissants, candles and an old fashioned cook stove. He constructed a cabin worthy of the harshest Buffalo winter storm. BTW if you click on the pictures they link to significantly larger versions there of.

It is bitter cold today. In the teens (-10 C) actually. There is a beautiful blanket of light fluffy snow. A perfect day to stay inside by the wood stove and work on my final exam.

BTW Geron presented interim results of the GRN163L trial at the American Society of Hematology meeting in San Francisco today. I'd like to conjecture that they talked about me as I received the dosing level of 4.8 mg/kg. It is pure conjecture though. There may have been several other patients at that level.

Thursday, December 04, 2008

Ups and Downs

Slowly but surely my MM protein expression is dying off. That's a good thing! Three cycles and three quarters gone. (another 30% reduction) I like that. The bionic arm is slowly learning to act human. The semester is quickly coming to an end and my Christmas cheer is all the more enhanced by the good news. We are minimalist when it comes to Christmas consumption, but I do love the new smells, music and festive lights. I get to dress up as a gingerbread man and act like a cheerful dork Friday. That aught to help my spirit. I guess a picture is in order.

My dear friend Sue who has graced me with her love and compassion, who has inspired me with her courage and perseverance passed away early yesterday morning at Hospice Buffalo. May your journey be filled with passion and love and guided by the grace of God. Here she is with that infectious smile in the Gilda's library. Peace be with you.

Protein expression going down perks me up as does Sue's smile, her memory and the fondness of all that support she brought the Wednesday evening Gilda's Wellness Group.