I have received numerous inquiries about my experience with GRN163L. Unfortunately my MM did progress toward the end of the 20 weeks I was on the trial. I withdrew from the trial and was looking forward to a drug free escape for the rest of the summer. It is obvious that a significant part of the disease progress occurred in my left humerus. I now have a nice titanium spike in my arm. To eliminate some the healing competition I immediately started radiation treatment to kill off the MM tumor near the break. Just the left humerus and rotator cuff area are getting zapped.Next is a Rev/low dose dex regimen scheduled to start in early September. The durability of which may be affected by the GRN163L therapy. Remember GRN is not an anti-tumor agent. It is an anti-MM stem cell agent. It is assumed the MM stem cell is a very small portion of the tumor burden. Only time will tell.

