Friday, January 30, 2009

Hope

We adopted a stray that took up residence under our porch a while ago. She is a beautiful extremely thin caramel calico in perfect health (according to the vet). She had a chip that complicated matters as the vet had to contact the registered owners while we waited oh so patiently with Hope still on the porch. (We didn't want to expose Marley to a possibly sick cat and didn't want to incur a vet bill for someone else's). I'm actually not a cat lover - just a lover of my cats. Cats tend to scare me a bit until I get to know them. Being a rural farm land kid most cats I encountered were not interested in being my friend and would let me know it, rather unexpectedly, in that lightning fast cat kind of way.

Hope now smells like she just got home from the salon, but is still clearing some of the under the porch dust from her sinuses. A nice juxtaposition. No AIDs, Leukemia, fleas or parasites, just under weight and ever so slightly frost bitten.

Our family has a "Bob" cat theme with a Dylan, Marley and now Hope. Bob Hope lived to 100 so some of that fortitude must have been passed on to our Hope (or at least that is hopefully true).

Sunday, January 18, 2009

Fantastic Voyage


Yes that would be us... you're on this voyage also or you wouldn't be reading this. Hows about a ship even smaller than the one Raquel Welch got shrunk into but plenty exciting all the same, probably revolutionary and certainly awe inspiring. I stumbled across a ScienceDaily (2009-01-16) article: Fantastic Voyage: Medical 'Mini-submarine' Invented To Blast Diseased Cells In The Body
Scientists developed a medical "mini-submarine" to blast diseased cells in the body. The blueprints for the submarine and a map of its proposed maiden voyage were developed earlier this year. Now the scientists will build and test-run the actual "machine" in human bodies.
The lead scientist, Dr. Peer, has some goals that resonate.

We are particularly interested in

1. Identifying key genes responsible for pluripotent hematopoietic stem cells self-renewal properties.

2. Studying the role of cell cycle regulators in proliferation, migration, and cytokine production in lymphocytes, macrophages and dendritic cells during inflammatory bowel diseases and rheumatoid arthritis .

3. Developing and studying novel approaches to target cancer stem cells.

4. Harnessing siRNAs and miRNAs as novel tools for drug discovery and for therapeutic applications.

Let hope his voyage is fantastic, incredible and highly relevant to what ails me.