Monday, March 30, 2009

Munching Continues

The predators called in last month to munch away at those pesky little MM cells are smiling along with me from ear to ear. I learned a few hours ago that my Laughing Plasma Cell's protein expression is a quarter of last months and about 6% of its peak 7 months ago.

If you're bored here are some detials. We did a little curcumin experiment. During cycle 6 (February) I did not take any curcumin but continued other minor supplements. My protein expression was up slightly but considered stable. This past month, cycle 7, I resumed taking 8 grams of C3 Complex curcumin in the morning approximately 12 hours after taking Revlimid. My myeloma (monoclonal or M-Spike) protein expression went down over 75%. I love this note on my labs: "Serum Protein Expression: very small M-Spike visible on gel but too small to quantitate." I'll take too small to quantitate any day! Although the ratio of my light chain expression (Kappa/Lambda) is ten times lower than 'normal' it is the first time it has had a value in years. It usually just says < 0.01 and the Kappa expression is listed as < 0.5 mg/L. It is now in the normal range, 7 mg/L.

As for my sense of welling being, believe it or not it is more closely related to my hemoglobin and hematocrit than anything else. They are just a tad low now. Of course being told that my elbow isn't attached to my shoulder is a bit bothersome. I find it rather unbelievable, but it does hurt like hell if I rotate my forearm just right. Life is Good!

3 comments:

Anonymous said...

LPC great progress for sure.
Any chance you would want to get back into the GRN163L trial now that with intermittant dosing they expect to get up into real serious Telomerase inhibition?
Best wishes.
Bob

L.P. Cells said...

I'll probably do several more cycles of Rev & curcumin with dose reduction of the Rev. Given a durable response GRN and/or other trials will be seriously considered.

Susie Hemingway said...

You seem to be doing so well..I was interested to read of Curcumin once again. All Good Wishes to you.